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KMID : 0380420160400020068
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Journal of Prventive Veterinary Medicine
2016 Volume.40 No. 2 p.68 ~ p.70
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Virucidal efficacy of a paraformaldehyde-containing fumigant against Avian influenza virus
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Cha Chun-Nam
Park Eun-Kee
Yoo Chang-Yeul
Jung Ji-Youn
Son Song-Ee
Kim Suk
Lee Hu-Jang
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Abstract
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In this study, the virucidal efficacy of a fumigant (35% paraformaldehyde) against avian influenza virus (AIV) was examined. After AIV suspensions had been deposited on stainless steel carriers, the dried carriers were exposed to the fumigant in a 300-m3 test room for 3 h. Thereafter, all carriers were submerged in a neutralizing solution to scrape off the surviving viruses, and the respective suspensions were diluted. Each dilution factor was respectively inoculated into the allantoic membrane of five 10-day-old embryos. After incubation, AIV viability in the collected allantoic fluids was examined and the EID50 was calculated. The fumigant inactivated ≥5.7log10EID50 of AIV and was nontoxic to the embryos.
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KEYWORD
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Fumigation, paraformaldehyde, avian influenza virus, virucidal efficacy
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